Klinefelter syndrome was first described in 1942 by Dr. Harry Klinefelter and colleagues in an endocrinology clinic at Massachusetts General Hospital in Boston, Massachusetts.
Men with Klinefelter syndrome are described as tall, slim, narrow shouldered, broad hipped with hypergonadotropic hypogonadism and small testes and recently the description had been expanded to include increased risk of the metabolism syndrome, type 2 diabetes and an unfavorably change in body composition.
Type 2 diabetes are more common in adolescents and adults with Klinefelter syndrome compared with the general population. Epidemiologic studies on Klinefelter syndrome have shown an increased risk of dying from diabetes or being admitted to the hospital with diabetes.
Type2 diabetes in Klinefelter syndrome
